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J Dermatol Sci. 2011 Jan;61(1):7-13. doi: 10.1016/j.jdermsci.2010.11.015. Epub 2010 Dec 5.

Epithelial-mesenchymal transition in the skin.

Author information

1
Department of Dermatology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan. motonaka@med.uoeh-u.ac.jp

Abstract

Epithelial-mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, and malignant cutaneous cancers, including squamous cell carcinoma and melanoma.

PMID:
21167690
DOI:
10.1016/j.jdermsci.2010.11.015
[Indexed for MEDLINE]

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