Format

Send to

Choose Destination
See comment in PubMed Commons below
J Surg Oncol. 2010 Dec 15;102(8):946-54. doi: 10.1002/jso.21653.

Optimum chemotherapy regimens for neoadjuvant therapy of hepatic colorectal metastases.

Author information

1
Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7305, USA.

Abstract

Resection of metastatic colorectal cancer hepatic lesions has gained support as surgical advances have made resections safer. Subsequently, the use of neoadjuvant therapy to cytoreduce tumors coupled with improved medical therapy has enhanced resection rates leading to improved outcomes. In "unresectable" disease, the addition of biologic therapies has further enhanced antitumor response, resulting in successful disease resection in certain patients. This review examines approaches to the neoadjuvant management of colorectal liver metastases with systemic therapies.

PMID:
21165997
DOI:
10.1002/jso.21653
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center