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IEEE Trans Ultrason Ferroelectr Freq Control. 2010 Dec;57(12):2839-43. doi: 10.1109/TUFFC.2010.1758.

A dual-modality probe utilizing intravascular ultrasound and optical coherence tomography for intravascular imaging applications.

Abstract

We have developed a dual-modality biomedical imaging probe utilizing intravascular ultrasound (IVUS) and optical coherence tomography (OCT). It consists of an OCT probe, a miniature ultrasonic transducer and a fixed mirror. The mirror was mounted at the head of the hybrid probe 45° relative to the light and the ultrasound beams to change their propagation directions. The probe was designed to be able to cover a larger area in blood vessel by IVUS and then visualize a specific point at a much finer image resolution using OCT. To demonstrate both its feasibility and potential clinical applications, we used this ultrasound-guide OCT probe to image a rabbit aorta in vitro. The results offer convincing evidence that the complementary natures of these two modalities may yield beneficial results that could not have otherwise been obtained.

PMID:
21156380
PMCID:
PMC3059782
DOI:
10.1109/TUFFC.2010.1758
[Indexed for MEDLINE]
Free PMC Article
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