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Neurol India. 2010 Nov-Dec;58(6):825-32. doi: 10.4103/0028-3886.73737.

Neuroform stent-assisted coiling of large and giant intracranial aneurysms: angiographic and clinical outcomes in 71 consecutive patients.

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1
Beijing Neurosurgical Institute, Capital Medical University, Beijing, People's Republic of China.

Abstract

BACKGROUND:

Large and giant aneurysms still remain a therapeutic challenge both surgically and endovascularly.

OBJECTIVE:

The authors report their clinical experience and follow-up results using Neuroform stent, as an adjunct in the treatment of large and giant aneurysms.

MATERIALS AND METHODS:

A total of 71 consecutive patients with 72 large or giant intracranial aneurysms were treated with the Neuroform stent-assisted coiling. Both sequential technique and parallel technique were used. In all cases, embolization was completed by packing the aneurysm sac with a variety of commercially available coils. The technical feasibility of the procedure, procedure-related complications, angiographic results, clinical outcome, and follow-up angiography were evaluated.

RESULTS:

In all the patients, the Neuroform stent system was delivered and deployed accurately, and occlusion was achieved. Immediate angiography demonstrated complete occlusion of the aneurysm in 59.7% of the patients, neck remnant in 26.4%, and incomplete occlusion in 13.9%. Procedure-related complication, morbidity, and mortality were 15.3, 4.2, and 1.4%, respectively. Favorable clinical outcome (modified Rankin Scale score 0-2) was observed in 83.3% of the patients (average follow-up time: 37.1 months). None of the treated aneurysm had rebleeding. Angiography follow-up was obtained in 81.7% (58/71 patients; 59/72 aneurysms; average follow-up time, 43.2 months). The overall recanalization rate was 28.8%. No delayed coil or stent migration was found. In-stent stenosis occurred as a delayed complication in one patient.

CONCLUSIONS:

The Neuroform stent-assisted coiling for large and giant intracranial aneurysms is safe and feasible with comparable incidences of morbidity and mortality.

PMID:
21150044
DOI:
10.4103/0028-3886.73737
[Indexed for MEDLINE]
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