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Plant Physiol Biochem. 2011 Feb;49(2):131-7. doi: 10.1016/j.plaphy.2010.10.008. Epub 2010 Nov 18.

Novel antifungal defensins from Nigella sativa L. seeds.

Author information

1
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya Str. 16/10, 117997 Moscow, Russian Federation. rea21@list.ru

Abstract

From seeds of Nigella sativa L. (Ranunculaceae), an endemic plant of Uzbekistan, two novel defensins named Ns-D1 and Ns-D2, were isolated and sequenced. The peptides differ by a single amino acid residue and show high sequence similarity to Raphanus sativus L. defensins Rs-AFP1 and Rs-AFP2. The Ns-D1 and Ns-D2 defensins display strong although divergent antifungal activity towards a number of phytopathogenic fungi. High antifungal activity of N. sativa defensins makes them promising candidates for engineering pathogen-resistant plants.

PMID:
21144761
DOI:
10.1016/j.plaphy.2010.10.008
[Indexed for MEDLINE]

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