Format

Send to

Choose Destination
BMC Biol. 2010 Dec 13;8:144. doi: 10.1186/1741-7007-8-144.

How the vertebrates were made: selective pruning of a double-duplicated genome.

Author information

1
Razavi Newman Center for Bioinformatics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. manning@salk.edu

Abstract

Vertebrates are the result of an ancient double duplication of the genome. A new study published in BMC Biology explores the selective retention of genes after this event, finding an extensive enrichment of signaling proteins and transcription factors. Analysis of their expression patterns, interactions and subsequent history reflect the forces that drove their evolution, and with it the evolution of vertebrate complexity.

PMID:
21144066
PMCID:
PMC3001425
DOI:
10.1186/1741-7007-8-144
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center