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Drugs R D. 2011;11(1):13-27. doi: 10.2165/11539760-000000000-00000.

Intra-articular injections for the treatment of osteoarthritis: focus on the clinical use of hyaluronic acid.

Author information

1
Department of Biological and Biomedical Sciences, Glasgow Caledonian University, Glasgow, UK. tommaso.iannitti@gmail.com

Abstract

Osteoarthritis (OA), also called degenerative joint disease, is the most frequently occurring chronic musculoskeletal disease, particularly affecting the aging population. The use of viscosupplementation, i.e. intra-articular (IA) hyaluronic acid (HA) drug therapy, to treat OA, is growing worldwide, due to important results obtained from several clinical trials, which reported IA HA-related improvements in functional activity and pain management. This review is an update of the IA use of this compound in the treatment of OA, with clinical evidence from the last few years being discussed and used to delineate new trends for the future.

PMID:
21142290
PMCID:
PMC3586124
DOI:
10.2165/11539760-000000000-00000
[Indexed for MEDLINE]
Free PMC Article

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