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Indian J Orthop. 2007 Jul;41(3):239-40. doi: 10.4103/0019-5413.33690.

Guillain-Barre syndrome: A possibility in a spinal cord injured patient.

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Yorkshire Regional Spinal Injury Centre, Pinderfields General Hospital, Wakefield, UK.


A 28-year-old male had paraplegia as a result of fracture dislocation of T12/L1 six years ago. He was functioning independently until four weeks ago, when he started complaining of trunkal paraesthesia which later progressed to include the upper extremities. The initial diagnosis was that of posttraumatic syringomyelia (PTS). While awaiting the MRI scan he developed weakness of upper limbs. The weakness restricted his self-care activities including transfers. The MRI did not show any evidence of syringomyelia. Neurological consultation and assessment yielded provisional diagnosis of Guillain-Barre syndrome (GBS). The patient was treated with immunoglobulins and regained 90% of his previous neurological status. This case is reported to raise awareness among clinicians to include the possibility of the GBS in the differential diagnosis of progressive neurological loss on top of existing neurological deficiency in spinal cord injured patients.


Guillain-Barre syndrome; progressive paralysis; spinal cord injury; syringomyelia

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