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J Fam Pract. 2010 Dec;59(12):709-10.

Clinical inquiries. Do intra-articular steroid injections affect glycemic control in patients with diabetes?

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Valley Family Medicine Residency, Renton, WA, USA.

Erratum in

  • J Fam Pract. 2011 Apr;60(4):180.


Yes, but the clinical importance is minimal. A single intra-articular steroid injection into the knee produces acute hyperglycemia for 2 or 3 days in patients with diabetes who otherwise have good glucose control (strength of recommendation [SOR]: B, small cohort studies). Intra-articular steroid injections into the shoulder may briefly raise postprandial (but not mean) glucose levels with larger and repeated doses (SOR: C, extrapolated from heterogeneous and mixed cohort studies).

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