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Acta Pharm. 2010 Sep;60(3):339-48. doi: 10.2478/v10007-010-0028-5.

Evaluation of binding properties of Plantago psyllium seed mucilage.

Author information

1
Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. majsaeedi@yahoo.com

Abstract

Mucilage extracted from Plantago psyllium seeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/m) of PVP. Investigated paracetamol tablets indicated that psyllium mucilage can retard the drug release.

PMID:
21134867
DOI:
10.2478/v10007-010-0028-5
[Indexed for MEDLINE]

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