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Nano Lett. 2011 Jan 12;11(1):279-85. doi: 10.1021/nl103873a. Epub 2010 Dec 6.

DNA tunneling detector embedded in a nanopore.

Author information

1
Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, UK.

Abstract

We report on the fabrication and characterization of a DNA nanopore detector with integrated tunneling electrodes. Functional tunneling devices were identified by tunneling spectroscopy in different solvents and then used in proof-of-principle experiments demonstrating, for the first time, concurrent tunneling detection and ionic current detection of DNA molecules in a nanopore platform. This is an important step toward ultrafast DNA sequencing by tunneling.

PMID:
21133389
PMCID:
PMC3020087
DOI:
10.1021/nl103873a
[Indexed for MEDLINE]
Free PMC Article

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