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Surg Obes Relat Dis. 2011 Jul-Aug;7(4):510-5. doi: 10.1016/j.soard.2010.09.011. Epub 2010 Sep 21.

Effect of sleeve gastrectomy on gastroesophageal reflux disease: a systematic review.

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Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.



Sleeve gastrectomy (SG) has increased in popularity as both a definitive and a staged procedure for morbid obesity. Gastroesophageal reflux disease (GERD) is a common co-morbid disease in bariatric patients. The effect of SG on GERD has not been well studied; thus, the goal of the present systematic data review was to analyze the effect of SG on GERD.


A systematic data search was conducted using Medline, EMBASE, the Cochrane Database, Scopus, and the gray literature for the Keywords "sleeve gastrectomy;" "gastroesophageal reflux;" and equivalents.


A total of 15 reports were retrieved. Two reports analyzed GERD as a primary outcome, and 13 included GERD as a secondary study outcome. Of the 15 studies, 4 showed an increase in GERD after SG, 7 found reduced GERD prevalence after SG, 3 included only the postoperative prevalence of GERD, and 1 did not include data on prevalence of GERD.


The evidence of the effect of SG on GERD did not consolidate to a consensus. The studies showed differing outcomes. Hence, dedicated studies that objectively evaluate GERD after SG are needed to more clearly define the effect of SG on GERD in bariatric patients.

[Indexed for MEDLINE]

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