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Int J Antimicrob Agents. 2010 Nov;36 Suppl 3:S8-14. doi: 10.1016/S0924-8579(10)70004-2.

Emerging carbapenemases: a global perspective.

Author information

1
Cardiff University, Heath Park Hospital, UK. WalshTR@Cardiff.ac.uk

Abstract

The celestial rise in antibiotic resistance among Gram-negative bacteria has challenged both the scientific and pharmaceutical sectors. The hallmark of this general increase is the unbridled dissemination of carbapenem resistance genes, namely KPC, OXA and metallo-β-lactamase variants. In particular, the media attention given to the NDM-1 metallo-β-lactamase has highlighted the global consequences of human behaviour on spreading antibiotic resistance.

PMID:
21129630
DOI:
10.1016/S0924-8579(10)70004-2
[Indexed for MEDLINE]

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