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Appl Phys Lett. 2010 Nov 1;97(18):183701. Epub 2010 Nov 3.

Displacement of particles in microfluidics by laser-generated tandem bubbles.

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Department of Mechanical Engineering and Materials Science, Duke University, P.O. Box 90300, Durham, North Carolina 27708, USA.


The dynamic interaction between laser-generated tandem bubble and individual polystyrene particles of 2 and 10 μm in diameter is studied in a microfluidic channel (25 μm height) by high-speed imaging and particle image velocimetry. The asymmetric collapse of the tandem bubble produces a pair of microjets and associated long-lasting vortices that can propel a single particle to a maximum velocity of 1.4 m∕s in 30 μs after the bubble collapse with a resultant directional displacement up to 60 μm in 150 μs. This method may be useful for high-throughput cell sorting in microfluidic devices.

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