Format

Send to

Choose Destination
Biomed Chromatogr. 2011 Jan;25(1-2):59-64. doi: 10.1002/bmc.1541. Epub 2010 Dec 1.

Towards clinical proteomics analysis.

Author information

1
Reseach Institute of Pharmaceutical Sciences, Musashino University, Nishitokyo-shi, Tokyo 202-8585, Japan. k-imai@musashino-u.ac.jp

Abstract

To understand accurate protein dynamics, a highly reproducible proteomics analytical method is required. The acquired thus knowledge will lead to the diagnosis, treatment and protection against diseases. This review deals with proteomics analysis from a view of sample pre-treatment, sensitivity and reproducibility of the methods, including two-dimensional polyacrylamide gel electrophoresis (2D-PAGE), liquid chromatography-tandem mass spectrometry (LC-MS/MS). and fluorogenic derivatization (FD)-LC-MS/MS.

PMID:
21121007
DOI:
10.1002/bmc.1541
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center