The first case of competitive heterogeneously catalyzed enantioselective hydrogenation of ketones

Katalin Balázsik; Kornél Szori; György Szollosi; Mihály Bartók

doi:10.1039/c0cc04110f

The first case of competitive heterogeneously catalyzed enantioselective hydrogenation of ketones

Chem Commun (Camb). 2011 Feb 7;47(5):1551-2. doi: 10.1039/c0cc04110f. Epub 2010 Nov 29.

Authors

Katalin Balázsik¹, Kornél Szori, György Szollosi, Mihály Bartók

Affiliation

¹ Stereochemistry Research Group of the Hungarian Academy of Sciences, H-6720 Szeged, Dóm tér 8, Hungary.

PMID: 21113549
DOI: 10.1039/c0cc04110f

Abstract

In competitive racemic hydrogenation of methyl benzoylformate (MBF) + ethyl pyruvate (EP) binary mixture over Pt/Al(2)O(3): k(MBF) > k(EP), but in competitive enantioselective hydrogenation k(MBF) < k(EP); the phenomenon verified for the first time is dependent on the adsorption strength of the surface complexes of various compositions (MBF-Pt, EP-Pt, MBF-CD-Pt, EP-CD-Pt, CD = cinchonidine).