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Bull Exp Biol Med. 2010 Jul;149(1):44-6.

Anticoagulation and antiplatelet effects of semax under conditions of acute and chronic immobilization stress.

[Article in English, Russian]

Author information

1
Laboratory of Defense Systems of Blood, Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow University, Russsia. mgrigorjeva@mail.ru

Abstract

The effects of semax on anticoagulant, fibrinolytic, and platelet components of the anticoagulation system were studied on albino rats under conditions of acute and chronic immobilization stress. Semax exhibited a protective antistress effect after repeated intranasal administration under conditions of hypercoagulation developing in response to immobilization stress of different degree. The effect manifested in stimulation of the anticoagulation system.

PMID:
21113455
[Indexed for MEDLINE]

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