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Vaccine. 2011 Jan 10;29(3):382-6. doi: 10.1016/j.vaccine.2010.11.006. Epub 2010 Nov 25.

Hospital initiation of a vaccinal schedule improves the long-term vaccinal coverage of ex-preterm children.

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Department of Neonatal Medicine, Nantes University Hospital, Nantes, France. sophie.denizot@chu-nantes.Fr


Preterm infants are experiencing delays in receiving routine schedule vaccines. We evaluated up-to-date immunisation status of 602 preterm infants at 5 and 24 months for DTCoqPolioHib and pneumococcal conjugate vaccine (defined by 3 and 4 doses, respectively). At 5 months, 39% (CI 95% [35-43]) of children were up-to-date for DTCoqPolioHib and 22% (CI 95% [19-26]) for pneumococcal conjugate, while at 24 months 67% (CI 95% [64-71]) were up-to-date for DTCoqPolioHib and 36% (CI 95% [32-40]) for pneumococcal conjugate. After adjustment for gestational age, a primary vaccine before discharge remained linked with a better vaccinal coverage (p<.005, OR=5.0; CI 95% [2.9-8.5]).

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