Development of benzothiazole 'click-on' fluorogenic dyes

Bioorg Med Chem Lett. 2011 Jan 1;21(1):320-3. doi: 10.1016/j.bmcl.2010.11.009. Epub 2010 Nov 5.

Abstract

'Click-on' fluorogenic reaction: a non-fluorescent benzothiazole with an electron-deficient alkyne group at 2-position reacts with azide containing molecules could form fluorescent adducts.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Alkynes / chemistry
  • Azides / chemistry
  • Benzothiazoles / chemistry*
  • Click Chemistry
  • Copper / chemistry
  • Fluorescent Dyes / chemistry*

Substances

  • Alkynes
  • Azides
  • Benzothiazoles
  • Fluorescent Dyes
  • Copper
  • benzothiazole