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Cell. 2010 Nov 24;143(5):677-81. doi: 10.1016/j.cell.2010.10.026.

What determines the specificity and outcomes of ubiquitin signaling?

Author information

1
Frankfurt Institute for Molecular Life Sciences, Goethe University School of Medicine, Main, Germany.

Abstract

Ubiquitin signals and ubiquitin-binding domains are implicated in almost every cellular process, but how is their functionality achieved in cells? We assess recent advances in monitoring the dynamics and specificity of ubiquitin networks in vivo and discuss challenges ahead.

PMID:
21111228
DOI:
10.1016/j.cell.2010.10.026
[Indexed for MEDLINE]
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