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Nanoscale. 2011 Feb;3(2):546-56. doi: 10.1039/c0nr00646g. Epub 2010 Nov 25.

Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications.

Author information

1
Department of Chemistry, Shands Cancer Center, University of Florida Genetics Institute, Gainesville, FL 32611-7200, USA.

Abstract

In recent years, nanomaterials have captured the attention of scientists from a wide spectrum of domains. With their unique properties, nanomaterials offer great promise for numerous applications, ranging from catalysis to energy harvesting and information technology. Functionalized with the desired biomolecules, nanomaterials can also be utilized for many biomedical applications. This paper summarizes recent achievements in the use of aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications. First, we discuss the features and properties of aptamers and then illustrate the use of aptamer-conjugated nanomaterials as sensing platforms and delivery vehicles, emphasizing how such integration can result in enhanced sensitivity and selectivity.

PMID:
21109879
DOI:
10.1039/c0nr00646g
[Indexed for MEDLINE]

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