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J Mol Biol. 1990 May 5;213(1):17-26.

Characterization of a G-protein beta-subunit gene from the nematode Caenorhabditis elegans.

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Netherlands Cancer Institute, Amsterdam.


The gene encoding the beta-subunit of guanine nucleotide binding regulatory proteins (G-proteins) has been cloned from the nematode Caenorhabditis elegans. The predicted 340 amino acid sequence matches the highly conserved amino acid sequences of previously isolated G-protein beta-subunits from mammals and Drosophila. The coding region of the C. elegans beta-subunit gene, which has been mapped to the C. elegans chromosome II, is interrupted by eight introns. Southern analysis indicates that C. elegans has only one beta-subunit gene. A 2.8 kb (1 kb = 10(3) bases or base-pairs) transcript derived from this gene could be detected.

[Indexed for MEDLINE]

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