Format

Send to

Choose Destination
See comment in PubMed Commons below
Science. 2010 Dec 17;330(6011):1693-5. doi: 10.1126/science.1197292. Epub 2010 Nov 25.

The cellular and physiological mechanism of wing-body scaling in Manduca sexta.

Author information

1
Department of Biology, Duke University, Durham, NC 27705, USA. hfn@duke.edu

Abstract

In animals, appendages develop in proportion to overall body size; when individual size varies, appendages covary proportionally. In insects with complete metamorphosis, adult appendages develop from precursor tissues called imaginal disks that grow after somatic growth has ceased. It is unclear, however, how the growth of these appendages is matched to the already established body size. We studied the pattern of cell division in the tobacco hornworm Manduca sexta and found that both the rate of cell division and the duration of growth of the wing imaginal disks depend on the size of the body in which they develop. Moreover, we found that both of these processes are controlled by the level and duration of secretion of the steroid hormone ecdysone. Thus, proportional growth is under hormonal control and indirectly regulated by the central nervous system.

PMID:
21109634
DOI:
10.1126/science.1197292
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center