Format

Send to

Choose Destination
Nat Chem. 2010 Dec;2(12):1084-8. doi: 10.1038/nchem.899. Epub 2010 Nov 23.

Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen.

Author information

1
Institute of Bioanalytical Chemistry, Dresden University of Technology, D-01062 Dresden, Germany. hermann.ehrlich@tu-dresden.de

Abstract

The minerals involved in the formation of metazoan skeletons principally comprise glassy silica, calcium phosphate or carbonate. Because of their ancient heritage, glass sponges (Hexactinellida) may shed light on fundamental questions such as molecular evolution, the unique chemistry and formation of the first skeletal silica-based structures, and the origin of multicellular animals. We have studied anchoring spicules from the metre-long stalk of the glass rope sponge (Hyalonema sieboldi; Porifera, Class Hexactinellida), which are remarkable for their size, durability, flexibility and optical properties. Using slow-alkali etching of biosilica, we isolated the organic fraction, which was revealed to be dominated by a hydroxylated fibrillar collagen that contains an unusual [Gly-3Hyp-4Hyp] motif. We speculate that this motif is predisposed for silica precipitation, and provides a novel template for biosilicification in nature.

PMID:
21107374
DOI:
10.1038/nchem.899
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center