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Conf Proc IEEE Eng Med Biol Soc. 2010;2010:6477-80. doi: 10.1109/IEMBS.2010.5627353.

Development of nanostructured magnetic capsules by means of the layer by layer technique.

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Department of Communication, Computer and System Sciences, Nanobiotechnology and Medical Informatics Laboratory, University of Genova, Italy.


Nanomagnetic particles have been already taken into account as drug carriers thank to the possibility to control their movement to a specific location where the treatment is required by means of high gradient magnetic fields (HGMF). In this work the layer-by-layer technique (LbL) and nanomagnetic particles were used to developed innovative nanostructured magnetic capsules (NSMC). Their potential application as magnetic drug carriers was investigated under the influence of both static and oscillating magnetic fields used respectively to control capsule displacement and shell permeability. The assembly process of the nanostructured magnetic capsules, its characterization by Quartz Crystal Microbalance (QCM), and the results obtained under the influence of the magnetic fields are presented.

[Indexed for MEDLINE]

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