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J Fr Ophtalmol. 2010 Dec;33(10):749-57. doi: 10.1016/j.jfo.2010.09.011. Epub 2010 Nov 18.

[Nutrition and age-related macular degeneration].

[Article in French]

Author information

1
Service de nutrition, institut Pasteur de Lille, 1, rue du Professeur-Calmette, BP 245, 59019 Lille cedex, France. Jean-michel.lecerf@pasteur-lille.fr

Abstract

Age-related macular degeneration is a growing burden disease with a high prevalence in elderly: it is the first cause of blindness in developped countries. It is a multifactorial disease with genetic factors and nutritional factors. Carotenoids, lutein and zeaxanthin are components of macular pigment and they have a filter role for blue light and an antioxidant role. Other nutritional factors might play a role as antioxidants: zinc, selenium, vitamin E, vitamin C… which lead to the ARED Study. It is the only one study with proven positive effects on the disease progression (stages 3 and 4). A high glycemic index increases oxidative stress. Long chain omega-3 polyunsaturated fatty acids have a protective effect. Available data are presented and discussed. These are new preventive issues.

PMID:
21093104
DOI:
10.1016/j.jfo.2010.09.011
[Indexed for MEDLINE]
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