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Acta Psychiatr Scand. 2011 Jul;124(1):6-17. doi: 10.1111/j.1600-0447.2010.01641.x. Epub 2010 Nov 24.

A comprehensive meta-analysis of the risk of suicide in eating disorders.

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Centro Medico Genneruxi, Via Costantinopoli 42, Cagliari, Italy.



Past meta-analyses on suicide in eating disorders included few available studies.


PubMed/Medline search for papers including sample n ≥40 and follow-up ≥5 years: 40 studies on anorexia nervosa (AN), 16 studies on bulimia nervosa (BN), and three studies on binge eating disorder (BED) were included.


Of 16,342 patients with AN, 245 suicides occurred over a mean follow-up of 11.1 years (suicide rate=0.124 per 100 person-years). Standardized mortality ratio (SMR) was 31.0 (Poisson 95% CI=21.0-44.0); a clear decrease in suicide risk over time was observed in recent decades. Of 1768 patients with BN, four suicides occurred over a mean follow-up of 7.5 years (suicide rate=0.030 per 100 person-years): SMR was 7.5 (1.6-11.6). No suicide occurred among 246 patients with BED (mean follow-up=5.3 years).


AN and BN share many risk factors for suicide: the factors causing lower suicide rates per person-year in BN compared to AN should be investigated.

[Indexed for MEDLINE]

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