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APMIS. 2010 Dec;118(12):991-3. doi: 10.1111/j.1600-0463.2010.02682.x. Epub 2010 Sep 14.

Comparison of IgG avidity assays in the confirmation of the diagnosis of cytomegalovirus primary infection.

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Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain.


We have compared three ELISA techniques and one chemiluminescence immunoassay technique for determining cytomegalovirus (CMV) immunoglobulin G (IgG) avidity in serum samples from patients with recent and past CMV infections. Sensitivity varied from 84.6% to 100%; and specificity from 78.6% to 100%. IgG avidity assays appear to be adequate additional tools for characterizing CMV infections.

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