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Pain Med. 2011 Jan;12(1):118-26. doi: 10.1111/j.1526-4637.2010.01012.x. Epub 2010 Nov 18.

A longitudinal assessment of painful diabetic peripheral neuropathy on health status, productivity, and health care utilization and cost.

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1
Health Sciences Practice, Kantar Health, 11 Madison Avenue, New York, NY 10010, USA. marco.dibonaventura@kantarhealth.com

Abstract

OBJECTIVE:

The aim of the current study was to examine the health outcomes of patients suffering from painful diabetic peripheral neuropathy (pDPN) over a 3-year period, relative to patients with diabetes but without neuropathic pain and controls.

DESIGN:

The current study included participants who completed three consecutive waves of the National Health and Wellness Survey (2006-2008). These participants were categorized into one of three groups: those with pDPN (N=290), those with diabetes but without pDPN ("diabetes without pDPN group"; N=1,037), and those not diagnosed with diabetes ("control group"; N=8,162).

OUTCOME MEASURES:

Health status (Short Form-12v2), work productivity (Work Productivity and Activity Impairment Questionnaire), and resource use were examined with repeated-measures models adjusting for demographic and clinical factors.

RESULTS:

The pDPN group reported significantly lower levels of physical quality of life. Moreover, physical quality of life scores for the pDPN group decreased at a significantly faster rate over a 3-year period relative to other groups. In addition, the pDPN patients reported significantly higher levels of impairment of work productivity and activity, greater resource use, and higher total 3-year per-patient costs.

CONCLUSIONS:

Confirming and expanding upon the literature, our results indicate a significantly worse trajectory of quality of life outcomes over time and long-term increased total costs for pDPN patients relative to non-pDPN diabetes patients and controls.

[Indexed for MEDLINE]

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