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Biochem Pharmacol. 1990 Apr 1;39(7):1205-12.

Heterogeneity of rat plasma albumin and drug binding.

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1
Department of Biopharmaceutics, Tokyo College of Pharmacy, Japan.

Abstract

Rat plasma albumin fractionated by Sephadex G-75 (superfine) gel filtration from freshly prepared rat plasma was further separated into three major fractions by chromatofocusing column chromatography. All the fractionated albumins had high binding affinity for the fluorescent probe 8-anilino-1-naphthalenesulfonic acid, as the model compound for acidic drugs, and were found to be immunologically identical.

PMID:
2108686
[Indexed for MEDLINE]
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