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J Appl Oral Sci. 2010 Sep-Oct;18(5):515-21.

Staining and calculus formation after 0.12% chlorhexidine rinses in plaque-free and plaque covered surfaces: a randomized trial.

Author information

1
School of Dentistry, Division of General Dentistry, Franciscan University Center, Santa Maria, RS, Brazil. fabriciobzanatta@yahoo.com.br

Abstract

OBJECTIVES:

Studies concerning side effects of chlorhexidine as related to the presence of plaque are scarce. The purpose of this study was to compare the side effects of 0.12% chlorhexidine gluconate (CHX) on previously plaque-free (control group) and plaque-covered surfaces (test group).

METHODS:

This study had a single-blind, randomized, split-mouth, 21 days-experimental gingivitis design, including 20 individuals who abandoned all mechanical plaque control methods during 25 days. After 4 days of plaque accumulation, the individuals had 2 randomized quadrants cleaned, remaining 2 quadrants with plaque-covered dental surfaces. On the fourth day, the individuals started with 0.12% CHX rinsing lasting for 21 days. Stain index intensity and extent as well as calculus formation were evaluated during the experimental period.

RESULTS:

Intergroup comparisons showed statistically higher (p<0.05) stain intensity and extent index as well as calculus formation over the study in test surfaces as compared to control surfaces. Thus, 26.19% of test surfaces presented calculus, whereas calculus was observed in 4.52% in control surfaces.

CONCLUSIONS:

The presence of plaque increased 0.12% CHX side effects. These results strengthen the necessity of biofilm disruption prior to the start of CHX mouthrinses in order to reduce side effects.

TRIAL REGISTRATION:

ClinicalTrials.gov NCT00818376.

PMID:
21085810
PMCID:
PMC4246385
DOI:
10.1590/s1678-77572010000500015
[Indexed for MEDLINE]
Free PMC Article

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