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Expert Rev Hematol. 2008 Dec;1(2):183-8. doi: 10.1586/17474086.1.2.183.

Diagnosis of antiphospholipid syndrome.

Author information

1
Lupus Research Unit, The Rayne Institute, King's College London School of Medicine at Guy's, King's and St Thomas' Hospitals, St Thomas' Hospital, London, UK. maria.bertolaccini@kcl.ac.uk

Abstract

Antiphospholipid syndrome is a multisystem autoimmune disease, characterized by recurrent vascular thrombosis and/or pregnancy losses in the presence of persistently positive antiphospholipid antibodies. In clinical practice, testing for anticardiolipin antibodies and lupus anticoagulant is mandatory for the laboratory diagnosis of antiphospholipid syndrome. Identification of patients with antiphospholipid syndrome is important, as prophylactic anticoagulant therapy may prevent thrombosis from recurring, and treatment during pregnancy can improve fetal and maternal outcome.

PMID:
21082923
DOI:
10.1586/17474086.1.2.183
[Indexed for MEDLINE]

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