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Bioinformatics. 2010 Dec 15;26(24):3140-2. doi: 10.1093/bioinformatics/btq602. Epub 2010 Nov 15.

iMAT: an integrative metabolic analysis tool.

Author information

1
The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv, Israel. zurhadas@post.tau.ac.il

Abstract

SUMMARY:

iMAT is an Integrative Metabolic Analysis Tool, enabling the integration of transcriptomic and proteomic data with genome-scale metabolic network models to predict enzymes' metabolic flux, based on the method previously described by Shlomi et al. The prediction of metabolic fluxes based on high-throughput molecular data sources could help to advance our understanding of cellular metabolism, since current experimental approaches are limited to measuring fluxes through merely a few dozen enzymes.

AVAILABILITY AND IMPLEMENTATION:

http://imat.cs.tau.ac.il/.

PMID:
21081510
DOI:
10.1093/bioinformatics/btq602
[Indexed for MEDLINE]

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