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Methods Mol Biol. 2011;693:75-87. doi: 10.1007/978-1-60761-974-1_5.

Autopsy and histological analysis of the transgenic mouse.

Author information

1
Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands. m.gijbels@gen.unimaas.nl

Abstract

Over the past decades, transgenic and knock-out mouse models have become common use in research laboratories. Detailed phenotypic characterization of such models is essential for understanding basic mechanisms of normal physiology and disease. Hereto, pathological examination is a very helpful tool. This chapter describes detailed procedures to perform autopsy and immuno-histological analysis of mice.

PMID:
21080275
DOI:
10.1007/978-1-60761-974-1_5
[Indexed for MEDLINE]

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