Format

Send to

Choose Destination
See comment in PubMed Commons below
J Clin Oncol. 2010 Dec 20;28(36):5301-10. doi: 10.1200/JCO.2010.30.3271. Epub 2010 Nov 15.

European Organisation for Research and Treatment of Cancer recommendations for planning and delivery of high-dose, high-precision radiotherapy for lung cancer.

Author information

1
Maastricht University Medical Center, GROW Research Institute, Department of Radiation Oncology (Maastro clinic), Dr Tanslaan 12, NL-6229 ET Maastricht, the Netherlands. dirk.deruysscher@maastro.nl

Abstract

PURPOSE:

To derive recommendations for routine practice and clinical trials for techniques used in high-dose, high-precision thoracic radiotherapy for lung cancer.

METHODS:

A literature search was performed to identify published articles considered both clinically relevant and practical to use. Recommendations were categorized under the following headings: patient selection, patient positioning and immobilization, tumor motion, computed tomography and [18F]fluorodeoxyglucose-positron emission technology scanning, generating target volumes, radiotherapy treatment planning, treatment delivery, and scoring of response and toxicity. The American College of Chest Physicians grading of recommendations was used.

RESULTS:

Recommendations were identified for each of the recommendation categories. Although most of the recommended techniques have not been evaluated in multicenter clinical trials, their use in high-precision thoracic radiotherapy and stereotactic body radiotherapy (SBRT) appears to be justified on the basis of available evidence.

CONCLUSION:

Recommendations to facilitate the clinical implementation of high-precision conformal radiotherapy and SBRT for lung tumors were identified from the literature. Some techniques that are considered investigational at present were also highlighted.

PMID:
21079134
DOI:
10.1200/JCO.2010.30.3271
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Atypon
    Loading ...
    Support Center