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J Am Soc Echocardiogr. 2011 Jan;24(1):60-74. doi: 10.1016/j.echo.2010.10.004. Epub 2010 Nov 13.

New equations and a critical appraisal of coronary artery Z scores in healthy children.

Author information

1
Division of Pediatric Cardiology, Laval University Hospital Centre, Faculty of Medicine, Laval University, Quebec, Quebec, Canada.

Abstract

BACKGROUND:

The aim of this study was to find the best model to obtain valid and normally distributed Z scores for coronary artery (CA) diameters in a large, heterogeneous population of healthy children.

METHODS:

Echocardiography was performed on 1,033 healthy children. Several regression models were tested with height, weight, body surface area, and aortic valve diameter. The computed Z scores were tested for normal distribution and stability.

RESULTS:

CA diameter was best predicted using regression with the square root of body surface area. The weighted least squares method yielded normally distributed and very stable Z-score estimates for all CA segments. In prepubertal children, aortic valve diameter was also a valid predictor of CA diameter.

CONCLUSIONS:

This study shows two valid methods to estimate Z scores for CA size in children of all ages. Such Z scores are important for risk stratification in patients with Kawasaki disease.

PMID:
21074965
DOI:
10.1016/j.echo.2010.10.004
[Indexed for MEDLINE]

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