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Methods Mol Biol. 2011;696:369-77. doi: 10.1007/978-1-60761-987-1_24.

LC/MS data processing for label-free quantitative analysis.

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1
Proteome Informatics Group, Swiss Institute of Bioinformatics, Geneva, Switzerland.

Abstract

In this chapter, we describe the use of SuperHirn and MSight, two complementary tools developed to the processing of label-free LC/MS data in view of the quantitation of proteomics samples. While MSight is mainly dedicated to the visualisation and navigation into LC/MS data, SuperHirn is specialised in peak detection, normalisation and alignment of LC/MS runs. These two tools can be used in a complementary way and one of the possible usages is described here.

PMID:
21063961
DOI:
10.1007/978-1-60761-987-1_24
[Indexed for MEDLINE]
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