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Br J Cancer. 2011 Jan 4;104(1):12-8. doi: 10.1038/sj.bjc.6605982. Epub 2010 Nov 9.

Childhood leukaemia, nuclear sites, and population mixing.

Author information

1
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Headington, Oxford, OX3 7LF, UK. leo.kinlen@gtc.ox.ac.uk

Abstract

The excess of childhood leukaemia (CL) in Seascale, near the Sellafield nuclear reprocessing site in rural NW England, suggested that an epidemic of an underlying infection, to which CL is a rare response, is promoted by marked population mixing (PM) in rural areas, in which the prevalence of susceptibles is higher than average. This hypothesis has been confirmed by 12 studies in non-radiation situations. Of the five established CL excesses near nuclear sites, four are associated with significant PM; in the fifth, the Krummel power station in Germany, the subject has not been thoroughly investigated.

PMID:
21063418
PMCID:
PMC3039801
DOI:
10.1038/sj.bjc.6605982
[Indexed for MEDLINE]
Free PMC Article

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