Effect of phenobarbital induction, charcoal treatment and storage on the spectral binding characteristics and NADPH-cytochrome P-450 reductase activity of hepatic microsomes

Biochem Pharmacol. 1990 Jan 15;39(2):393-6. doi: 10.1016/0006-2952(90)90040-r.

Authors

D L Crankshaw¹, R R Erickson, J L Holtzman

Affiliation

¹ Research Service, Veterans Administration Medical Center, Minneapolis, MN 55417.

PMID: 2105734
DOI: 10.1016/0006-2952(90)90040-r

No abstract available

MeSH terms

Animals
Benzphetamine / pharmacology
Binding Sites
Charcoal*
Enzyme Induction / drug effects
Ethylmorphine / pharmacology
Male
Microsomes, Liver / drug effects*
Microsomes, Liver / enzymology
NADPH-Ferrihemoprotein Reductase / metabolism*
Oxidation-Reduction
Phenobarbital / isolation & purification
Phenobarbital / pharmacology*
Rats
Time Factors
Tissue Preservation

Substances

Benzphetamine
Charcoal
NADPH-Ferrihemoprotein Reductase
Ethylmorphine
Phenobarbital