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Transpl Infect Dis. 2011 Apr;13(2):161-7. doi: 10.1111/j.1399-3062.2010.00581.x. Epub 2010 Nov 5.

BK virus encephalitis with thrombotic microangiopathy in an allogeneic hematopoietic stem cell transplant recipient.

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Serviço Transplantação Progenitores Hematopoiéticos, Instituto Português de Oncologia de Lisboa, Lisbon, Portugal.


BK virus (BKV) infection occurs most often in immunocompromised hosts, in the setting of renal or bone marrow transplantation. Hemorrhagic cystitis is the commonest manifestation but in recent years infections in other organ systems have been reported. We report an unusual case of biopsy-proven BKV encephalitis in a hematopoietic stem cell transplant patient who subsequently developed thrombotic microangiopathy. As far as we know, this is the first report of such an association in a transplant patient.

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