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Clin Vaccine Immunol. 2011 Jan;18(1):173-5. doi: 10.1128/CVI.00325-10. Epub 2010 Nov 3.

Correlation between serum and plasma antibody titers to mycobacterial antigens.

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1
Graduate Division of Biomedical Sciences, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Abstract

The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays.

PMID:
21047999
PMCID:
PMC3019788
DOI:
10.1128/CVI.00325-10
[Indexed for MEDLINE]
Free PMC Article
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