Abstract
Disseminated cryptococcosis and recurrent oral candidiasis was presented in a-heterosexual AIDS patient. Candida tropicalis (C.tropicalis) was isolated from the oral pseudomembranous plaques and Cryptococcus neoformans (C. neoformans) was isolated from maculopapular lesions on body parts (face, hands and chest) and body fluids (urine, expectorated sputum, and cerebrospinal fluid). In vitro drug susceptibility testing on the yeast isolates demonstrated resistance to fluconazole acquired by C. tropicalis which was a suggestive possible root cause of recurrent oral candidiasis in this patient.
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Adult
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Antifungal Agents / pharmacology
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Body Fluids / microbiology
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Candida tropicalis / isolation & purification*
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Candidiasis, Oral / complications
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Candidiasis, Oral / diagnosis*
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Candidiasis, Oral / microbiology
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Cryptococcosis / complications
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Cryptococcosis / diagnosis*
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Cryptococcosis / microbiology
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Cryptococcus neoformans / isolation & purification*
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Drug Resistance, Fungal*
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Fluconazole / pharmacology*
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Humans
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Male
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Microbial Sensitivity Tests
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Mouth Mucosa / microbiology
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Mouth Mucosa / pathology
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Skin / microbiology
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Skin / pathology
Substances
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Antifungal Agents
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Fluconazole