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AORN J. 2010 Nov;92(5):509-18. doi: 10.1016/j.aorn.2010.01.020.

Evidence for using chlorhexidine gluconate preoperative cleansing to reduce the risk of surgical site infection.

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Department of Surgery, Medical College of Wisconsin, Milwaukee, USA.


Surgical site infections are associated with significant patient morbidity and mortality and are the third most frequently reported health care-associated infection. A suggested risk reduction strategy has been the preadmission shower or skin cleansing with chlorhexidine gluconate (CHG). Although older clinical trials question the clinical efficacy of cleansing with CHG, recent evidence-based scientific and clinical studies support two types of CHG application (ie, a 2% CHG-coated cloth or 4% CHG soap) using a standardized, timed process before hospital admission as an effective strategy for reducing the risk of postoperative surgical site infection.

[Indexed for MEDLINE]

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