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Nano Lett. 2010 Dec 8;10(12):4858-62. doi: 10.1021/nl1025826. Epub 2010 Nov 1.

Virus-PEDOT nanowires for biosensing.

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1
Department of Chemistry, University of California, Irvine, California 92697-2025, United States.

Abstract

The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition. The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.

PMID:
21038915
PMCID:
PMC3116991
DOI:
10.1021/nl1025826
[Indexed for MEDLINE]
Free PMC Article
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