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Semin Cell Biol. 1990 Jun;1(3):197-209.

Genes involved in the development of the peripheral nervous system of Drosophila.

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Department of Zoology, University of Washington, Seattle 98195.


The development of the peripheral nervous system (PNS) requires the activity of a number of genes. The neurogenic and the proneural genes are necessary in the earliest phase; their mutations lead to hyperplasia and partial or total elimination of the PNS respectively. Some of these mutations also affect other developmental processes. Other mutations affect later events: cut transforms one type of sensory organ into another; numb alters the fate of the components of a single sensory organ. We will describe the effects of the best studied mutations on PNS development and discuss the possible role of the wild type genes.

[Indexed for MEDLINE]

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