Format

Send to

Choose Destination
Nucleic Acids Res. 2011 Jan;39(Database issue):D301-8. doi: 10.1093/nar/gkq1069. Epub 2010 Oct 29.

RBPDB: a database of RNA-binding specificities.

Author information

1
Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.

Abstract

The RNA-Binding Protein DataBase (RBPDB) is a collection of experimental observations of RNA-binding sites, both in vitro and in vivo, manually curated from primary literature. To build RBPDB, we performed a literature search for experimental binding data for all RNA-binding proteins (RBPs) with known RNA-binding domains in four metazoan species (human, mouse, fly and worm). In total, RPBDB contains binding data on 272 RBPs, including 71 that have motifs in position weight matrix format, and 36 sets of sequences of in vivo-bound transcripts from immunoprecipitation experiments. The database is accessible by a web interface which allows browsing by domain or by organism, searching and export of records, and bulk data downloads. Users can also use RBPDB to scan sequences for RBP-binding sites. RBPDB is freely available, without registration at http://rbpdb.ccbr.utoronto.ca/.

PMID:
21036867
PMCID:
PMC3013675
DOI:
10.1093/nar/gkq1069
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center