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Arch Pediatr. 2011 Jan;18(1):41-4. doi: 10.1016/j.arcped.2010.09.015. Epub 2010 Oct 30.

[Bordetella bronchiseptica-associated acute chest syndrome in a child with sickle cell disease].

[Article in French]

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  • 1Laboratoire de microbiologie, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, 149 rue de Sèvres, Paris, France.


We describe a case of acute chest syndrome associated with Bordetella bronchiseptica pneumonia in a child with sickle cell disease. B. bronchiseptica is recognized as an important pathogen of the respiratory tract for a large variety of animal species. This zoonotic agent has been frequently associated with chronic and recurrent infections. In humans, the bacterium acts as an opportunistic pathogen affecting mostly immunocompromised patients or those with preexisting respiratory diseases. This case and literature review provides an opportunity to discuss the risk factors, treatment, follow-up, and prevention of such zoonotic infections in the context of a lack of cross-protection of new pertussis vaccines.

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