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J Neurol Sci. 2011 Jan 15;300(1-2):157-9. doi: 10.1016/j.jns.2010.10.007. Epub 2010 Oct 29.

Post-streptococcal vasculopathy with evolution to Degos' disease.

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1
Barrow Neurological Institute, 350 W Thomas Road, Phoenix, AZ 85013, United States. sandipan.pati@chw.edu

Abstract

Degos' disease or malignant atrophic papulosis is a rare disseminated occlusive vasculopathy affecting the skin, gastrointestinal tract, central nervous system, and less often other organ systems. The exact etiology of this vasculopathy has not been established. Infections, autoimmune disease and coagulation defects have been proposed as underlying pathogenic mechanisms, but none have been confirmed. Here, we report the clinical, radiological and histopathologic features of Degos' disease in a 41-year-old man following streptococcal throat infection. Prior postulated hypothesis as post-infectious immunologic mechanism may be further supported by this case.

PMID:
21035145
DOI:
10.1016/j.jns.2010.10.007
[Indexed for MEDLINE]
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