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J Pediatr Nurs. 2010 Dec;25(6):500-4. doi: 10.1016/j.pedn.2009.07.002. Epub 2009 Aug 21.

Adherence to antiretroviral therapy in pediatric patients with human immunodeficiency virus (HIV-1).

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1
Division of Allergy, Immunology and Infectious Diseases, New Brunswick, NJ, USA. burackgd@umdnj.edu

Abstract

The evaluation of HIV treatment adherence is essential to manage the development of resistant mutations, treatment failure, and disease progression in patients with HIV-1 infection; however, none of the commonly used measures of treatment adherence have been found to be accurate. The objective of this study was to evaluate three treatment adherence measures (caregiver reports, pharmacy refill, and appointment maintenance data) in association with viral load suppression in pediatric patients with HIV-1 infection. Although viral suppression was not found to be significantly associated with adherence defined by any single measure, treatment adherence could be predicted if all three measures were in agreement.

PMID:
21035017
DOI:
10.1016/j.pedn.2009.07.002
[Indexed for MEDLINE]
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