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J Am Coll Cardiol. 2010 Nov 2;56(19):1535-41. doi: 10.1016/j.jacc.2010.01.076.

Biomarkers in acute aortic dissection and other aortic syndromes.

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1
School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom.

Abstract

Acute aortic syndromes have an incidence of >30 per million per annum and a high mortality without definitive treatment. Survival may relate to the speed of diagnosis. Although pain is the most common symptom, there is a large fraction of patients in whom the diagnosis may be mistaken or overlooked. Currently, a high index of clinical suspicion is the chief prompt that diverts a patient into a definitive algorithm of imaging investigations. Although there is no point-of-care biochemical test that can be reliably used to positively identify dissection, biomarkers are available that could accelerate the diagnostic pathway and thereby expedite treatment.

PMID:
21029872
DOI:
10.1016/j.jacc.2010.01.076
[Indexed for MEDLINE]
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